The modified nucleosides of tRNAs. II. Synthesis of 2'-O-methylcytidylyl (3'-5') cytidine.
نویسندگان
چکیده
The synthesis of 2'-O-methylcytidylyl (3'-5')cytidine by the triester method using as protecting groups, 2,2,2-trichloroethyl for phosphate hydroxyl group, p-chlorophenyoxyacetyl for 5-hydroxyl group, methoxymethylidene for 2',3'-cis-diol system, and benzoyl for the exo-amino group of cytidine is presented. The obtained product was characterised by UV, electrophoresis, chromatography and an enzymatic digestion.
منابع مشابه
Chemical and Conformational Diversity of Modified Nucleosides Affects tRNA Structure and Function
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ورودعنوان ژورنال:
- Nucleic acids research
دوره 2 6 شماره
صفحات -
تاریخ انتشار 1975